Dr. S. K. GHOSH

Dr. S. K. GHOSH
Dr. S. K. GHOSH
...
Professor
Pharmaceutical Science

Profile

Education:

  1. Bachelor’s Degree: B.Pharm (BIT, Mesra)
  2. Master’s Degree: M.Pharm (BIT, Mesra)
  3. Ph.D.: Pharmacy (Jadavpur University, Calcutta)
  4. Other: FIC (Calcutta)

Professional Experience: Teaching & Research: 33 years

Areas of Interest/ Specialization: Medicinal and synthetic chemistry

Research Projects:

  • File NO: EMR/2017/000708/HS "Design, Microwave Assisted Syntheisis and Antmalanal Evaluation of Hybrid Para-Amino- Benzoic Acid-I,3,5-triazine derivatives" DST Sponsored for 3 years. Sanctioned in December 2018 (Fund mobilized) Rs.3465000/ In collaboration with RMRC, Dibrugarh.
  • No. BT/330/NE/TBP/2012 Dtd. 29.04.13 Synthesis of Hybrid class pheylthiazole 1,3,5- Triazine derivatives as novel antifolate for Pf-DHFR- TS Inhibition 3 years DBT, New Delhi.
  • No. BT/237/NE/TBP/2011 Dtd. 25.04.12 Investigation of anticancer and antiulcer activity of the selected ethno-medicinal plants of Mizoram and further isolation and characterization of their chemical constitutents 3 years DBT, New Delhi.
  • No. SR/S0/HS- 125/2010 Dtd. 10.05.12 “Synthesis of Hybrid 4-Aminoquinoline – 1,3,5 – Triazine Derivatives and Evaluation of their Antimalarial Activity” 3 Years DST, New Delhi.

Ph.D Scholars:

Sl. No.

Name

Topic

Status

(On-going /Completed)

1

Ms. TC. Lalhriatpuii

Phytochemical and pharmacological evaluation of selected medicinal plants of Mizoram

Completed

2010

2

Mr. Nikhil Kumar

Fabrication and biopharmaceutical characterization of microencapsulate controlled drug delivery system composed of Assam bora rice as possible muchoadhesive backbone

Completed

2011

3

Mr. Prashant Kumar

Antimalarial and antibacterial evaluation of some synthesized substituted phenylthiazole 1,3,5-triazine derivatives

Completed

2011

4

Mr. Hans Raj Bhat

Synthesis and antimalarial evaluation of hybrid 4-aminoquinoline triazine derivatives

Completed

2013

5

Mr. Brijesh Singh

Synthesis and evaluation of few colon specific prodrugs

Completed

2013

6

Ms. Arti S. Shivliha

Fast dissolving dosage forms of some antiepileptic drugs: Formulation and evaluation

Completed

2014

7

Mr. Dipankar Saha

Phytochemical and pharmacological evaluation of some Indian medicinal plants having antidiabetic activity

Completed

2015

8

Mr. Kumar Sourav Dey

Some Indian medicinal plants from North East: A comprehensive phytochemical and pharmacological study of their potential use as hypoglycaemic agent.

Completed

9

Ms. Indrani Bhattacharya

Stress degradation studies and development of validated stability indicating RP-HPLC method for simultaneous estimation of antihypertensive and diuretic drug in combine dosage form and identification of degradants

Completed

2017

10

Ms. R. Laliumpuii

Phytochemical and pharmacological screening of some medicinal plants from Mizoram.

Completed

2018

11

Mr. Junmoni Kalita

Design, synthesis and antimalarial evaluation of some phenylthiazolyl triazine derivatives against Plasmodium falciparum.

Completed

2018

12

Ms. Supriya Sahu

Insilico studies, synthesis and antimalarial evaluation of hybrid phenylthiazolyl triazine derivatives

Completed

2017

13

Mr. Surajit Tamuli

Comparative studies of efficacy and effect on oxidative stress of some clinically used antihypertensive agents in the patients of North East India

Completed

2017

14  Mr. Sanjay Kumar Yadav

Phyto-pharmacological evaluation of some ethnomedicinal plants for antidiarrhoeal activity

Completed

2017

15 Ms. Arpita Das

Design, insilico screening and antimalarial evaluation of some microwave assisted synthesised phenylthiazolyl 1,3,5-triazine derivatives

Ongoing

16 Ankita Kashyap

In-silico screening, synthesis and antimalarial evaluation of some PABA substituted triazine derivatives as PfDHFR inhibitors

Ongoing

17 Maibam Beebina
Chanu

Phytochemical and pharmacological evaluation of
antidiabetic plants used by traditional healers in Manipur.

Ongoing

18 Anshul Sakhya

Holistic evaluation of adaptogenic potential of the Benincasa hispida Thum. fruits.

Ongoing

19 Nayana Adhikari

Synthesis and antimalarial evaluation of hybrid PABA- glutamic acid conjugated triazine derivatives as Pf-DHFR inhibitor.

Ongoing

Publications

Research Publications:

  1. Brijesh Singh, D.K. Patel and S.K. Ghosh. A reverse phase high performance liquid chromatographic method for determination of chlorthalidone in pharmaceutical formulation. IJJPS 2009; 2(1):24-29ISSN: 0975-1491.
  2. B Singh, D.K. Patel and S.K. Ghosh. Development of Reverse-Phase HPLC Method for Simultaneous Analysis of Metoprolol Succinate and Hydrochlorothiazide in a Tablet Formulation. Tropical Journal of Pharmaceutical Research, 2009; 8(6): 539-54ISSN: 1596-9827 (IF: 0.338).
  3. Mohan A., Ghosh S.K. New method for spectrophotometric estimation of new anti epileptic drugs in solid dosage form. Asian J. Research Chem. 2009, 2(3): 322-324 ISSN: 0974-4169.
  4. Archana Uppal, Anita Singh, Prashant Gahtori, Surajit Kumar Ghosh and Mohammad Zaki Ahmad. Antidepressants: Current Strategies and Future Opportunities. Current Pharmaceutical Design 2010; 16(38):4243-53ISSN: 1381-6128 (IF: 4.774).
  5. Mohan A. and S.K Ghosh. Fast dissolving tablets: Past, Present and Future. Indian Drugs 2010; 47(6):5-11ISSN: 0019-462X.
  6. Arti Mohan, S.K.Ghosh. Study to observe permeation enhancement of oxcarbazepine after complexation. Deccan J. Pharmaceutics and Cosmetology 2010, 1(1): 20-28.
  7. Nikhil K Sachan, S.K Ghosh and A. Bhattacharya. Evaluation of glutinnous rice starch based matrix microbeads using scanning electron microscopy. J. Chem. Pharm. Res. 2010; 2(3):433-452ISSN: 0975-7384.
  8. Sachan N.K, Ghosh S.K. and Late Bhattacharya, A, Pharmaceutical utility of Assam Bora rice for controlled drug delivery. Accepted for publication in Word Applied Sciences Journal 2011, 14 (11)1687-1695ISSN: 1818-4952.
  9. Jewel Junejo, Surajit Kumar Ghosh, Mutahar Shaikh, Prashant Gahtori andUdaya Pratap Singh, Facile Synthesis, Antibacterial Activity and Molecular Properties Prediction of Some New 1,3-dihydroimidazol-2-thione Derivatives. Letters in Drug Design & Discovery 2011, 8 (8):763-768ISSN: 1570-1808 (IF: 0.668).
  10. P. Gahtori, A. Singh, S.K. Ghosh, A. Das and U. Archana. Synthesis of Some Substituted Phenylthiazolyl 1,3,5-Triazine Derivatives. Asian Journal of Chemistry 2011; 23(3): 1189 –1192.ISSN: 0970-7077 (IF: 0.247).
  11. Kumar Saurav Dey, S.K. Ghosh. Evaluation of antibacterial activity of some substituted phenyl benzaldimine derivatives. Der Pharmacia lettre. 2010, 2(3): 209-205ISSN: 0975 –5071.
  12. Dipankar Saha, Ghosh S.K., Trishna Das, Habibur Rahman. Effect of Adiantumcaudatumin streptozotocin induced diabetes mellitus in rats. Int. Res J Pharm. App Sci. 2011, 1(1): 9-15ISSN-2277-4149.
  13. Prashant Gahtori, Surajit Kumar Ghosh, Brijesh Singh, Udaya Pratap Singh, Hans Raj Bhat, Archana Uppal. Synthesis, SAR and antibacterial activity of hybrid chloro, dichloro-phenylthiazolyl-s-triazines. Saudi Pharmaceutical Journal, 2012 Science Direct Communication/ Doi: 10.1016/j.jsps.2011.05.003)ISSN: 1319-0164 (IF: 0.130).
  14. Prashant Gahtori and Surajit K Ghosh Design, synthesis and SAR exploration of hybrid 4-Chlorophenylthiazolyl-s-triazine as potential antimicrobial agents. Journal of Enzyme Inhibition and Medicinal Chemistry, 2012 Informa Healthcare/http://cats.informa.com/PTS/go?t=rl&o=oa&m=587418)ISSN : 1475-6366 (IF: 1.574).
  15. Sachan N.K., Ghosh S.K., Bhattacharya, A. Differential scanning calorimetric analysis of drug polymer interaction in glutinous rice based microbeads. Asian Journal of Chemistry, 2012, 24 (5)ISSN No: 0970-7077 (IF: 0.247).
  16. Prashant Gahtori, Surajit K. Ghosh, Pratap Parida, Anil Prakash, Kabita Gogoi, Hans Raj Bhat, Udaya Pratap Singh. Antimalarial evaluation and docking studies of hybrid phenylthiazolyl-1,3,5-triazine derivatives: A novel and potential antifolate A novel lead for Pf DHFR-TS inhibition Experimental Parasitology 2012, DOI:10.1016/J.exppara 2011.12.014ISSN: 0014-4894 (IF: 2.093) 
  17. Surajit Kumar Ghosh, Ashmita Saha, Bornali Hazarika, Udaya Pratap Singh, Hans Raj Bhat and Prashant Gahtori. Design, Facile Synthesis, Antibacterial Activity and Structure-Activity Relationship of Novel Di- and Tri-Substituted 1,3,5-Triazines Letters in Drug Design & Discovery, 2012, 1570-1808/12 (IF: 0.668).
  18. Hans Raj Bhat, Surajit K. Ghosh, Anil Prakash, Kabita Gogoi, Udaya Pratap Singh. In-vitro antimalarial activity and molecular docking analysis of 4-aminoquinoline clubbed 1, 3, 5-triazine derivatives. Letters in Applied Microbiology 2012, DOI: 10.1111/j.1472-765X.2012.03234.xISSN: 1472-765X (IF: 1.647).
  19. Nikhil K Sachan, S.K. Ghosh, Anupam K Sachan, Sandeep K Singh. Livelihood Empowerment through Ecological Rationalization and Commodification in Natural Area Destinations. American Journal of Social Issues & Humanities. 2012, 2(6): 368-374ISSN: 2276 – 6928.
  20. Bhat H.R., Singh U.P., Gahtori P., Ghosh S.K., Gogoi Kabita, Prakash A., Singh R.K. Design, synthesis, in vitro antimalarial activity and docking studies of novel bifunctional hybrids derived from 4-aminoquinoline and 1,3,5-triazine against wild and mutant malaria parasites. RSC Advances, 2013, DOI: 10.1039/C2RA21915H
  21. Bhat H.R., Pandey P., Ghosh S.K., Singh U.P. Development of 4-aminoquinoline-1,3,5-triazine conjugates as potent antibacterial agent through facile synthetic route. Medicinal Chemistry Research, 2013, DOI: 10.1007/s00044-013-0521-8 ISSN: 1554-8120 (IF: 1.61).
  22. Nikhil K. Sachan, Seema Pushkar, Anupam K. Sachanand, S.K. Ghosh. Thermal Stability and Drug-Excipient Compatibility Studies of Peppermint and Caraway Oils for Formulation of Chewable Tablets, Asian Journal of Chemistry; 2013, 25(8): 5930-5934ISSN: 0970-7077(IF: 0.247).
  23. Seema Pushkar, Nikhil K Sachan, S.K. Ghosh. Particle characterization of pre-compressed granules for tablet fabrication using a novel pharmaceutical excipient. Indian Streams Research Journal,   2013, 3(1): 1-15ISSN:-2230-7850 (IF: 0.2105).
  24. Sandipan Dasgupta, Bhaskar Mazumder, Surajit K. Ghosh and Surendra S. Kaurav Solid lipid nanoparticles (SLNs) for topical delivery of aceclofenac by using xanthan gum: Ex vivo and in vivo evaluation. Current Drug Delivery, 2013, 10(6): 656-666 ISSN: 1875-5704 (IF: 4.9).
  25. I. Bhattacharyya, S.P. Bhattacharyya, C. Kyal, P. Choudhury, B. Dhakal, S.K. Ghosh, Estimation and Validation of Stability Indicating Uv Spectrophotometric Method for the Determination of Guaifenesin in Presence of its Degradant Products. Int J Pharm Pharm Sci, 2013, 5, (1), 262-268 ISSN- 0975-1491.
  26. Hans Raj Bhat, Udaya Pratap Singh, Prashant Gahtori, Surajit Kumar Ghosh, Kabita Gogoi, Anil Prakash and Ramendra K. Singh 4-Aminoquinoline-1,3,5-triazine: Design, synthesis, in vitro antimalarial activity and docking studies. New Journal of Chemistry 2013, DOI: 10.1039/c3nj00317e (IF 2.92).
  27. A. Mohan, Ghosh S.K. “Comparative permeation evaluation of some new antiepileptic drugs” AJADD 2013, 1(4): 552-564ISSN: 2321- 547x.
  28. Arti Mohan, S.K. Ghosh. Development and validation of UV/visible spectrophotometric method for the estimation of oxcarbazepine in bulk and pharmaceutical formulations” RRJPA 2013, 2(4): 9-12ISSN: 2321-0812.
  29. Arti Mohan, S.K. Ghosh. Development and validation of UV/visible spectrophotometric method for the estimation of lamotrigine in bulk and pharmaceutical formulations. AJPCT 2013, 2(11): 9-12ISSN: 1246-1251.
  30. Sandipan Dasgupta, Surajit K. Ghosh, Subhabrata Ray, Surendra Singh Kaurav, Bhaskar Mazumder "In vitro & in vivo Studies on Lornoxicam Loaded Nanoemulsion Gels for Topical Application" Current Drug Delivery, 2014, 11, 132-138 ISSN: 1875-5704 (IF:4.9).
  31. Hans Raj Bhat, Udaya Pratap Singh, Prashant Gahtori, Surajit Kumar Ghosh, Kabita Gogoi, Anil Prakash and Ramendra K. Singh "Synthesis, Docking, In Vitro and In Vivo Antimalarial Activity of Hybrid 4-aminoquinoline–1,3,5-triazine Derivatives Against Wild and Mutant Malaria Parasites" 2014 Chem Bio Drug Des doi: 10.1111/cbdd.12490ISSN (IF 2.50).
  32. Kumar Saurav Dey, Surajit Kumar Ghosh, Sorra Sandhya, Joyeeta Talukdar and Dipankar Saha ‘Assessment of In vitro Antioxidant potential and In vivo Anti-diabetic Activity on Streptozotocin-induced Diabetic Rats of Rumex maritimus L’. Asian Journal of Biochemical and Pharmaceutical Research 2014, 4(2): 164-170ISSN: 2231-2560.
  33. Jun Moni Kalita, Surajit Kumar Ghosh, Supriya Sahu, Mayurakhi Dutta, Hans Raj Bhat. Docking and crystal structure analysis of some phenyl thiazolyl triazine derivatives with quadrapole mutant PFDHFR-TS enzyme and their synthesis. World Journal of Pharmacy and Pharmaceutical Sciences 2015, 4(02): 1040-1049ISSN 2278-4357.
  34. B. Indrani, S.K. Ghosh ‘Development and validation of stability indicating rp-hplc method for determination of atenolol and hydrochlorthiazide in combined solid dosage form’ International Journal of Pharmacy and Pharmaceutical Sciences 2015, 7(2): 489-492ISSN- 0975-1491.
  35. Joydeb Acharjee, Anirban Ghoshal, Surajit Kumar Ghosh. Microwave-assisted synthesis: Need of the hour. World Journal of Pharmacy and Pharmaceutical Sciences 2015, 4(06):1741-1749ISSN 2278-4357.
  36. Hans Raj Bhat, Udaya Pratap Singh, Anjali Thakur, Surajit Kumar Ghosh, Kabita Gogoi, Anil Prakash, Ramendra K. Singh. Synthesis, antimalarial activity and molecular docking of hybrid 4-aminoquinoline-1,3,5-triazine derivatives. Experimental Parasitology. 2015, 157: 59-67ISSN: 0014-4894 (IF: 2.093)
  37. Qualitative phytochemical screening and evaluation of in-vitro antioxidant activity of callicarpa arborea roxb, an ethnomedicinal plant of Mizoram, northeast India Ghosh S.K., Lalawmpuii, Lalhriatpuii TC, Lalzikpuii, Lalengliani, K., AJPCR. 2015, 8,202-205ISSN: 0974-2441
  38. Hypoglycemic and antihyperlipidemic effects of adiantum caudatum in alloxan Induced diabetes in rats Surajit Kumar Ghosh, Dipankar Saha, Trishna Das, Shanti Bhushan Mishra. AJPCR. 2016, 1,339-341ISSN: 0974-2441
  39. Design, synthesis and antimalarial screening of some hybrid 4- aminoquinoline-triazine derivatives against pf-DHFR-TS Surajit Kumar Ghosh, Supriya Sahu, Junmoni Kalita, M. Dutta, H. R. Bhat. Experimental parasitology.  2016, 163, 38-45 I.F. 2.093 ISSN: 0014-4894
  40. Junmoni Kalita, Surajit K Ghosh, Supriya Sahu, Mayurakhi Dutta. A statistical analysis to find out an appropriate docking method, Asian journal of Pharmaceutical and clinical research 2015, 8(1), 158-160 ISSN: 0974-2441.
  41. Prashant Gahtori, Rahul Pandey, Vinod Kumar, Surajit Kumar Ghosh, Aparoop Das Jun Moni Kalita, Supriya Sahu, Anil Prakash, Divya Ranjan Bhattacharyya. Toward resistance‐compromised DHFR inhibitors part 1:Combined structure/ligand‐based virtual screenings and ADMETox profiling. Chemometrix, 2016, 30(8), 462-481 ISSN: 0886-9383 IF: 1.8.
  42. Sanjay Yadav, Sanjib Das, SK Ghosh, NP Yadav Antidiarrhoeal evaluation of traditionally used Ziziphus oenoplia (L.) Mill root, International Journal of Herbal Medicine 2016, 4(4), 98-102 ISSN: 2321-2187.
  43. Dr. Sanjib Das, Dr. Surajit. K. Ghosh and Sanjay Kumar Yadav, Antispasmodic effect of methanolic extract of ziziphus oenoplia (l.) Mill. Root bark, European Journal of Biomedical and Pharmaceutical sciences 2016, 3(9), 345-348 ISSN 2349-8870.
  44. Supriya Sahu, Surajit K. Ghosh, Anirban Ghoshal, Junmoni Kalita, Prashant Gahtori, Divya R. Bhattacharyya, Microwave assisted synthesis, antimalarial screening andstructure–activity relationship exploration of some phenylthiazolyl-triazine derivatives against dihydrofolate reductaseMed Chem Res 2016 DOI 10.1007/s00044-016-1714-8, ISSN:1554-8120 (Online) IF 1.436.
  45. Bhattacharyya Indrani, S.Basak, A.Maity, S.K.Ghosh. Isolation and characterization of acid and base drgradation products in Atenolol and Hydrochlorothiazide and a validated selective stability indicating HPLC-UV method for their quantification. International Journal of Advances in Pharmaceutical Analysis. 2015, 5(2), 36-41 ISSN: 2277-9353 IF: 0.876
  46. Kalita JM, Ghosh SK, Sahu S, Dutta M, Bhat HR. Docking and crystal structure analysis of some phenyl thiazolyl triazine derivatives with quadrapole mutant Pfdhfr-ts enzyme and their synthesis.World journal of pharmacy and pharmaceutical science. 2015, 4(2), 1040-1049. ISSN: 2278-4357 SJIF: 2.786.
  47. B.Hazarika, S.K.Ghosh, A Das, N.Sharma, JM. Kalita, SK. Sharma. Molecular docking studies of some hybrid phenylthiazolyl 1,3,5-triazine derivatives with PfDHFR enzyme. World journal of pharmacy and pharmaceutical science. 2016 5(9) 1782-1788. ISSN: 2278-4357 SJIF: 2.786.
  48. Jun Moni Kalita, Surajit Kumar Ghosh, Supriya Sahu, Mayurakhi Dutta. Rational design and microwave assisted synthesis of some novel phenyl thiazolyl clubbed s-triazine derivatives as antimalarial antifolate. Future Journal of Pharmaceutical Sciences 2017, 3, 11- 17 ISSN: 2314-7245.
  49. Anshul Shakya, Hans Raj Bhat, Surajit Kumar Ghosh. Update on Nitazoxanide: A Multifunctional Chemotherapeutic Agent. Current Drug Discovery Technologies, 2018, 15 201-213.
  50. Ankita Kashyap, Nayana Adhikari, Arpita Das, Anshul Sakhya, Surajit Kumar Ghosh, Uday Pratap Singh, Hansraj Bhat. Review on synthetic chemistry and antibacterial importance of thiazole derivatives. Current drug discovery technologies. 2018, 15, 214-228.
  51. Lalawmpuii R, Lalhriatpuii TC, Lalzikpuii K, Ghosh SK, Qualitative phytochemical screening and evaluation of in-vitro antioxidant activity of Callicarpa arborea Roxb. An ethnomedicinal plant of Mizoram. Asian journal of Pharmaceutical and Clinical Research. 2015, 8(5), 203-205. ISSN: 0974-2441
  52. R.Lalawmpuii, T.C. Lalhriatpuii, S.K.Ghosh. Invitro anticancer activity of Callicarpa arborea and Buettneria aspera Colebr a traditional medicinal plants from Mizoram, North East India, European journal of biomedical and pharmaceutical Sciences. 2017, 4(3) 362-367 ISSN: 2349-8870     IF: 4.918
  53. Aparoop Das, Anshul Shakya, Surajit Kumar Ghosh, Udaya Pratap Singh, Hans Raj Bhat “A Review of Phytochemical and Pharmacological Studies of Inula Species”, Current Bioactive Compounds, 2019, DOI: 10.2174/1573407215666190207093538 ISSN (Online): 1875-6646
  54. Arpita Das, Surajit Kumar Ghosh, Hans Raj Bhat, Junmoni Kalita, Ankita Kashyap, Nayana Adhikari, Insilico study, synthesis and antimalarial evaluation of hybrid phenyl thiazole 1,3,4- triazine derivatives, Current Bioactive Compounds, 2019 DOI: 10.2174/1573407215666190308154139 ISSN (Online): 1875-6646
  55. Supriya Sahu, Surajit Kumar Ghosh, Prashant Gahtori, Udaya Pratap Singh, Hans Raj Bhat In silico ADMET study, docking, synthesis and antimalarial evaluation of thiazole-1,3,5-triazine derivatives as Pf-DHFR inhibitor, Pharmacological Reports, 2019, DOI: 10.1016/j.pharep.2019.04.006. ISSN: 1734-1140 IF: 2.787
  56. Shakya A., Chaudary S.K., Garabadu D., Bhat H.R., Kakoti B.B., Ghosh S.K. A comprehensive review on preclinical diabetic models, Current Diabetes Reviews. 2019 DOI : 10.2174/1573399815666190510112035 ISSN:1875-6417
x

S.K. Ghosh

6:53 am (1 day ago)
   
to me
Dear Gunadeep
Pl find below three papers of mine for uploading in my profile publication. Hope you will do the needful
regards

1

 Qualitative phytochemical screening and evaluation of in-vitro antioxidant activity of callicarpa arborea roxb, an ethnomedicinal plant of Mizoram, northeast India  Lalawmpuii, Lalhriatpuii TC, Lalzikpuii, Lalengliani, K, Ghosh S.K. AJPCR. 2015, 8,202-205 ISSN: 0974-2441

 

2

Hypoglycemic and antihyperlipidemic effects of adiantum caudatum in alloxan Induced diabetes in rats Dipankar Saha, Surajit Kumar Ghosh, Trishna Das, Shanti Bhushan Mishra. AJPCR. 2016, 1,339-341 ISSN: 0974-2441

 

3

Design, synthesis and antimalarial screening of some hybrid 4- aminoquinoline-triazine derivatives against pf-DHFR-TS Supriya Sahu, Surajit Kumar Ghosh, Junmoni Kalita, M. Dutta, H. R. Bhat. Experimental parasitology.  2016, 163, 38-45 I.F. 2.093 ISSN: 0014-4894

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